The recently established, Center for Human Genomics and Precision Medicine at the School of Medicine and Public Health, is to lead a large-scale expansion of the University's activities in applied genomics and personalized medicine. The CHGPM's multifaceted application of genome sciences to clinical medicine encompasses basic, translational and clinical research as well as educational activities and community outreach. The Center now is entering a phase of rapid growth and is hiring a Human Genome Analyst for its Clinical Genomics Core.
The Scientist will function, as a key member of the Center's Clinical Genomics Core. The primary responsibility of the Human Genome Analyst is to support the Center's clinical research activities, which focus on innovative uses of `omic technologies in clinical care. In this regard, the Senior Genome Analyst will play a major role in the Center's gene discovery-oriented Undiagnosed Diseases Program. Protected time may be available for independent research relevant to the Center's mission. Principle duties include:
Laboratory/Research-Related Activities (85%) - Analyze and interpret candidate variants and candidate disease genes obtained from exome, genome, transcriptome, and other `omics analyses; assess their clinical relevance; help establish phenotype-genotype links; and generate and/or review clinical test reports. - As a member of the Clinical Genomics Core, provide expert consultative advice on variant interpretation and research study design to Center faculty as well as other UW clinicians and researchers. - Participate in development and evaluation of gene discovery protocols, variant annotation pipelines, and reporting templates. - Contribute to the development and implementation of new molecular diagnostic technologies. - Contribute to Center publications and presentations as well as assist in grant applications. - Develop independent research projects.
Training and Outreach Activities (15%) - Assist in the education of graduate and medical students, clinical trainees and UW MSc Genetic Counseling students. - Participate in the development of Center educational outreach events.
- An MD and/or PhD in human genetics/genomics or a related field is required.
- A minimum of two years' post-graduate experience in a molecular diagnostics/genome analysis environment is strongly preferred.
- A strong research background in gene discovery is preferred.
- Robust interpersonal and organizational abilities, strong written and verbal communication skills, and a talent for working independently and multitasking efficiently are expectations.
- Applicants who are board-certified or board-eligible in Laboratory Genetics and Genomics or Clinical Molecular Genetics and by the American Board of Medical Genetics and Genomics are preferred as well as applicants who hold equivalent foreign certification in molecular diagnostics.
Additional Salary Information: Minimum Annual Salary is $60,000
Internal Number: 98154
About UW-Madison School of Medicine and Public Health
UW-Madison has a robust human genetics/genomics community that supports the oldest and largest NIH-funded training graduate program in genetics, an MSc genetic counselling program, and ABMG-accredited fellowship programs. We benefit from a strong clinical and scientific infrastructure, including a 13-faculty clinical/metabolic genetics group, Departments of Medical Genetics and Genetics, the Carbone Comprehensive Cancer Center, the Waisman Center, the Genome Center of Wisconsin, and the UW Hospital and Clinics. In addition, over the next two years we expect to recruit 15+ new Centeraffiliated faculty with expertise in human genomics and/or precision medicine. Members of the Center have access to all of the benefits of a preeminent public research university that is 6th in the nation in research funding. The University of Wisconsin is known for its beautiful lakeside setting in the capitol city of Madison that boasts a high quality of life with excellent schools, affordable housing, low crime, clean air and abundant recreational and cultural opportunities.